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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPRD1A
All Species:
43.03
Human Site:
Y265
Identified Species:
72.82
UniProt:
Q96P16
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P16
NP_060640.2
312
35720
Y265
K
E
H
K
L
E
E
Y
K
R
K
L
A
R
V
Chimpanzee
Pan troglodytes
XP_001136630
316
36166
Y269
K
E
H
K
L
E
E
Y
K
R
K
L
A
R
V
Rhesus Macaque
Macaca mulatta
XP_001105423
312
35728
Y265
K
E
H
K
L
E
E
Y
K
R
K
L
A
R
V
Dog
Lupus familis
XP_866582
318
36360
Y271
K
E
H
K
L
E
E
Y
K
R
K
L
A
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDS4
312
35682
Y265
K
E
H
K
L
E
E
Y
K
R
K
L
A
R
V
Rat
Rattus norvegicus
XP_001056597
417
46600
Y370
K
E
H
K
L
E
E
Y
K
R
K
L
A
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512622
400
45577
Y353
K
E
H
K
L
E
E
Y
K
R
K
L
A
R
V
Chicken
Gallus gallus
Q5ZM30
268
30818
L222
V
D
D
A
C
M
L
L
A
D
Y
N
G
R
L
Frog
Xenopus laevis
NP_001088920
325
36694
Y278
K
E
K
K
L
E
E
Y
K
H
K
L
A
R
V
Zebra Danio
Brachydanio rerio
NP_955850
335
38090
Y288
R
E
K
K
L
E
E
Y
K
Q
K
L
A
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396379
332
37569
Y285
A
Q
A
T
L
E
D
Y
K
E
K
L
K
K
V
Nematode Worm
Caenorhab. elegans
P34281
315
36355
E261
E
N
V
R
M
S
I
E
H
H
E
K
L
C
R
Sea Urchin
Strong. purpuratus
XP_779930
352
40189
Y304
S
V
K
K
L
E
E
Y
K
D
R
L
E
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05543
409
46470
T317
K
N
E
V
V
E
K
T
D
S
E
H
K
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
99.6
98.1
N.A.
98.7
73.8
N.A.
71.2
78.2
64
60.9
N.A.
N.A.
49
24.1
46
Protein Similarity:
100
98.7
100
98.1
N.A.
99.3
74.3
N.A.
74.7
83.3
80.3
78.2
N.A.
N.A.
66.8
47.2
63.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
86.6
80
N.A.
N.A.
46.6
0
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
86.6
93.3
N.A.
N.A.
66.6
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
0
0
8
0
0
0
65
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
8
0
0
0
8
0
8
15
0
0
0
0
0
% D
% Glu:
8
65
8
0
0
86
72
8
0
8
15
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
50
0
0
0
0
0
8
15
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
65
0
22
72
0
0
8
0
79
0
72
8
15
8
0
% K
% Leu:
0
0
0
0
79
0
8
8
0
0
0
79
8
0
8
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
0
50
8
0
0
79
8
% R
% Ser:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% S
% Thr:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
8
8
8
8
8
0
0
0
0
0
0
0
0
0
79
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
79
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _